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Belzutifan is really a CYP2C19 substrate. Coadministration with CYP2C19 inhibitors might improve incidence or severity of adverse effects. Keep track of for anemia and hypoxia and decrease belzutifan dose as advised.modafinil will minimize the extent or effect of fruquintinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use